Across TCGA patient cohorts, PAQR9 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PAQR9-associated genes across cancer lineages are FASN, INPP4B, and ATM. Each is linked with PAQR9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAQR9-to-partner and partner-to-PAQR9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR9→partner) and Y-score (partner→PAQR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.300	+2.000	.038	.030	3	2
UCEC	INPP4B →	-0.287	-3.584	.015	.002	3	2
UCEC	ATM →	-0.546	-3.446	.001	.005	3	2
UCEC	Caspase-7-cleavedD198 →	+0.661	+1.827	.002	.015	3	2
UCEC	4E-BP1 →	+0.364	+2.247	<.001	.001	3	2
UCEC	C-Raf →	+0.209	+2.906	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

PAQR9 survival (RNA) · tumor vs normal (RNA) · all PAQR9 data types