Across TCGA cell cohorts, PAQR9 mutation is significantly associated with the RNA expression of many other genes, with 102 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PAQR9-associated genes across cancer lineages are NEU2, APCS, and ACER1. Each is linked with PAQR9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAQR9-to-partner and partner-to-PAQR9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR9→partner) and Y-score (partner→PAQR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	NEU2 →	+0.015	+4.643	<.001	.004	3	1
LUNG_SCLC	APCS →	+0.042	+4.643	<.001	.004	3	1
LUNG_SCLC	ACER1 →	+0.069	+4.044	<.001	.009	3	1
LUNG_SCLC	KRTAP19-5 →	+0.752	+4.269	<.001	.005	3	1
CNS	SCGB1C1 →	+0.242	+4.981	<.001	.008	3	1
LUNG_NSCLC_LUAD	G6PC →	+0.062	+4.212	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 102 associations by consensus.

Exploration

PAQR9 survival (RNA) · tumor vs normal (RNA) · all PAQR9 data types