PAQR8

Across TCGA cell cohorts, PAQR8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,135 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PAQR8-associated GO terms across cancer lineages are Negative thymic T cell selection, Negative T cell selection, and Cytokinesis. Each is linked with PAQR8 in more than 7 cancer types. Because this analysis shows association rather than direction, both PAQR8-to-partner and partner-to-PAQR8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative thymic T cell selection grouped by PAQR8-low versus PAQR8-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR8→partner) and Y-score (partner→PAQR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative thymic T cell selection →	+1.100	+1.402	.001	.007	3	8
BLOOD_Myeloma	Negative T cell selection →	+1.495	+1.341	<.001	<.001	3	7
BLOOD_Lymphoma	Cytokinesis →	+0.039	+0.910	.002	.009	3	7
UPPER_AERODIGESTIVE_TRACT	Branched-chain amino acid catabolic process →	+0.070	+0.890	.002	.001	2	7
STOMACH	Intestinal hexose absorption →	+0.214	+1.742	.002	.003	3	6
CNS	Negative regulation of glial cell migration →	+0.157	+0.661	.003	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,135 associations by consensus.

Negative thymic T cell selection by PAQR8 expression — OVARY

Explore this box plot interactively →