PAQR7

Across TCGA patient cohorts, PAQR7 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PAQR7-associated genes across cancer lineages are STAT5a, VHL, and Smad1. Each is linked with PAQR7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAQR7-to-partner and partner-to-PAQR7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT5a grouped by PAQR7-low versus PAQR7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR7→partner) and Y-score (partner→PAQR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT5a →	+0.499	+3.000	.031	.037	3	1
UCEC	VHL →	-1.391	-3.000	<.001	.036	3	1
UCEC	Smad1 →	+0.232	+3.000	.010	.037	2	1
UCEC	Ku80 →	+0.313	+3.013	.022	.019	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

STAT5a by PAQR7 expression — UCEC

Explore this box plot interactively →