PAQR7

Across TCGA cell cohorts, PAQR7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,623 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PAQR7-associated GO terms across cancer lineages are Regulation of cell-substrate adhesion, Wound healing, and Regulation of focal adhesion assembly. Each is linked with PAQR7 in more than 11 cancer types. Because this analysis shows association rather than direction, both PAQR7-to-partner and partner-to-PAQR7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-substrate adhesion grouped by PAQR7-low versus PAQR7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR7→partner) and Y-score (partner→PAQR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-substrate adhesion →	+0.131	+1.563	<.001	<.001	3	12
BONE	Wound healing →	+0.130	+1.617	<.001	<.001	3	12
BONE	Regulation of focal adhesion assembly →	+0.164	+1.663	<.001	<.001	3	11
BONE	Regulation of cell-substrate junction assembly →	+0.164	+1.663	<.001	<.001	3	11
BONE	Negative regulation of actin filament polymerization →	+0.131	+1.357	<.001	<.001	3	11
BONE	Positive regulation of plasma membrane repair →	+0.395	+2.116	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,623 associations by consensus.

Regulation of cell-substrate adhesion by PAQR7 expression — BONE

Explore this box plot interactively →