PAQR7

Across TCGA cell cohorts, PAQR7 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PAQR7-associated genes across cancer lineages are OR6C68, ZNRF4, and C22orf42. Each is linked with PAQR7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAQR7-to-partner and partner-to-PAQR7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C68 grouped by PAQR7-low versus PAQR7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR7→partner) and Y-score (partner→PAQR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR6C68 →	+0.042	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ZNRF4 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	C22orf42 →	+0.023	+3.554	.001	.007	3	1
LARGE_INTESTINE	USP17L4 →	+0.017	+3.632	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR6C68 by PAQR7 expression — SKIN

Explore this box plot interactively →