PAQR6

Across TCGA patient cohorts, PAQR6 mutation is significantly associated with the RNA expression of many other genes, with 191 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible PAQR6-associated genes across cancer lineages are RNU1-154P, SETP11, and RN7SL65P. Each is linked with PAQR6 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAQR6-to-partner and partner-to-PAQR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-154P grouped by PAQR6-low versus PAQR6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR6→partner) and Y-score (partner→PAQR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU1-154P →	+0.304	+4.588	<.001	.008	3	2
SKCM	SETP11 →	+0.094	+4.661	<.001	.004	3	2
SKCM	RN7SL65P →	+0.152	+4.594	<.001	.008	3	2
SKCM	RPS3AP17 →	+0.046	+5.199	<.001	.003	3	2
HNSC	RNU6-591P →	+0.510	+7.948	<.001	<.001	3	2
HNSC	MIR1255B2 →	+1.108	+6.468	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 191 associations by consensus.

RNU1-154P by PAQR6 expression — BLCA

Explore this box plot interactively →