PAQR6

Across TCGA cell cohorts, PAQR6 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PAQR6-associated genes across cancer lineages are OR13D1, XKRX, and TBC1D28. Each is linked with PAQR6 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAQR6-to-partner and partner-to-PAQR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13D1 grouped by PAQR6-low versus PAQR6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR6→partner) and Y-score (partner→PAQR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR13D1 →	+0.044	+3.066	.008	.006	3	1
BLOOD_Leukemia	XKRX →	+0.238	+3.675	<.001	.005	3	1
BLOOD_Leukemia	TBC1D28 →	+0.053	+2.926	<.001	.009	3	1
BLOOD_Leukemia	CFAP97D2 →	+0.292	+3.717	.006	.003	3	1
LARGE_INTESTINE	ADRA1A →	+0.234	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR1C1 →	+0.096	+4.684	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR13D1 by PAQR6 expression — BLOOD_Leukemia

Explore this box plot interactively →