PAQR5

Across TCGA cell cohorts, PAQR5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,563 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PAQR5-associated GO terms across cancer lineages are Podocyte development, Regulation of cellular response to hypoxia, and Nodal signaling pathway. Each is linked with PAQR5 in more than 6 cancer types. Because this analysis shows association rather than direction, both PAQR5-to-partner and partner-to-PAQR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Podocyte development grouped by PAQR5-low versus PAQR5-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR5→partner) and Y-score (partner→PAQR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Podocyte development →	+0.180	+0.960	<.001	.001	3	7
OVARY	Regulation of cellular response to hypoxia →	+0.094	+1.150	.001	.003	3	6
OVARY	Nodal signaling pathway →	+0.202	+1.559	<.001	.004	3	6
SOFT_TISSUE	Maintenance of protein localization in organelle →	+0.099	+0.806	.001	.002	3	6
SKIN	Positive regulation of intracellular protein transport →	+0.050	+0.777	.003	.003	3	6
STOMACH	Regulation of modification of synaptic structure →	+0.077	+1.101	.008	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,563 associations by consensus.

Podocyte development by PAQR5 expression — LUNG_SCLC

Explore this box plot interactively →