Across TCGA cell cohorts, PAPSS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,562 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PAPSS2-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Vesicle cargo loading, and Regulation of cell-substrate junction organization. Each is linked with PAPSS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PAPSS2-to-partner and partner-to-PAPSS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAPSS2→partner) and Y-score (partner→PAPSS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	COPII-coated vesicle cargo loading →	+0.159	+2.684	<.001	<.001	3	10
BONE	Vesicle cargo loading →	+0.099	+2.428	<.001	<.001	3	10
BONE	Regulation of cell-substrate junction organization →	+0.144	+2.533	<.001	<.001	3	9
BONE	Substrate adhesion-dependent cell spreading →	+0.188	+2.881	<.001	<.001	3	9
BONE	Protein localization to vacuole →	+0.084	+3.156	.001	<.001	3	9
BONE	Establishment of protein localization to vacuole →	+0.074	+2.283	.002	.002	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,562 associations by consensus.

Exploration

PAPSS2 survival (RNA) · tumor vs normal (RNA) · all PAPSS2 data types