PAPPA-AS2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PAPPA-AS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,277 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PAPPA-AS2-associated proteins across cancer lineages are PRRX1, PAPPA, and AEBP1. Each is linked with PAPPA-AS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PAPPA-AS2-to-partner and partner-to-PAPPA-AS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAPPA-AS2→partner) and Y-score (partner→PAPPA-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPRRX1 →+0.535+0.429.004.00434
PDACPAPPA →+0.442+0.425<.001<.00134
UCECAEBP1 →+0.490+0.434<.001.00634
HNSCFKBP7 →+0.526+0.697<.001<.00134
UCECLGALS1 →+0.501+0.554.002.00634
HNSCARHGEF17 →+0.331+0.951<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,277 associations by consensus.

Exploration