PAPOLG

Across TCGA cell cohorts, PAPOLG RNA expression is significantly associated with the go_rna of many other GO terms, with 5,001 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PAPOLG-associated GO terms across cancer lineages are Positive regulation of mRNA metabolic process, Regulation of mRNA stability, and Negative regulation of gene expression, epigenetic. Each is linked with PAPOLG in more than 16 cancer types. Because this analysis shows association rather than direction, both PAPOLG-to-partner and partner-to-PAPOLG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA metabolic process grouped by PAPOLG-low versus PAPOLG-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAPOLG→partner) and Y-score (partner→PAPOLG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of mRNA metabolic process →	+0.061	+0.519	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA stability →	+0.056	+0.570	.001	.004	3	16
STOMACH	Negative regulation of gene expression, epigenetic →	+0.076	+0.578	<.001	<.001	3	16
BLOOD_Myeloma	mRNA destabilization →	+0.062	+0.883	.001	<.001	3	16
STOMACH	Protein modification by small protein removal →	+0.055	+0.740	.003	.001	3	16
LUNG_SCLC	Regulation of centrosome duplication →	+0.099	+0.591	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,001 associations by consensus.

Positive regulation of mRNA metabolic process by PAPOLG expression — STOMACH

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