Across TCGA cell cohorts, PAPOLB RNA expression is significantly associated with the go_rna of many other GO terms, with 1,254 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PAPOLB-associated GO terms across cancer lineages are Centrosome cycle, Negative regulation of gene expression, epigenetic, and Microtubule organizing center organization. Each is linked with PAPOLB in more than 7 cancer types. Because this analysis shows association rather than direction, both PAPOLB-to-partner and partner-to-PAPOLB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAPOLB→partner) and Y-score (partner→PAPOLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Centrosome cycle →	+0.079	+0.031	<.001	.002	3	7
BONE	Negative regulation of gene expression, epigenetic →	+0.081	+0.033	<.001	.005	2	8
LUNG_SCLC	Microtubule organizing center organization →	+0.073	+0.030	<.001	.003	3	6
BONE	Heterochromatin formation →	+0.085	+0.034	<.001	.002	2	7
BONE	Epigenetic regulation of gene expression →	+0.070	+0.027	.001	.004	2	7
BONE	Nucleic acid transport →	+0.096	+0.029	.003	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,254 associations by consensus.

Exploration

PAPOLB survival (RNA) · tumor vs normal (RNA) · all PAPOLB data types