PAPOLA

Across TCGA patient cohorts, PAPOLA RNA expression is significantly associated with the RNA expression of many other genes, with 20,547 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PAPOLA-associated genes across cancer lineages are PPP4R3A, TRIP11, and PRORP. Each is linked with PAPOLA in more than 33 cancer types. Because this analysis shows association rather than direction, both PAPOLA-to-partner and partner-to-PAPOLA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAPOLA versus PPP4R3A in UVM, with a Pearson correlation of 0.97.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAPOLA→partner) and Y-score (partner→PAPOLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	PPP4R3A →	+1.631	+1.450	<.001	<.001	3	34
UVM	TRIP11 →	+1.540	+1.449	<.001	<.001	3	34
UVM	PRORP →	+0.928	+1.440	<.001	<.001	3	34
UVM	SMCHD1 →	+1.629	+1.418	<.001	<.001	3	34
UVM	CAND1 →	+1.366	+1.335	<.001	<.001	3	34
UVM	RNGTT →	+1.348	+1.351	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,547 associations by consensus.

PAPOLA vs PPP4R3A — UVM

Explore this scatter interactively →