PAOX

Across TCGA cell cohorts, PAOX RNA expression is significantly associated with the go_rna of many other GO terms, with 3,881 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PAOX-associated GO terms across cancer lineages are Putrescine biosynthetic process, Positive regulation of amine metabolic process, and Golgi vesicle transport. Each is linked with PAOX in more than 14 cancer types. Because this analysis shows association rather than direction, both PAOX-to-partner and partner-to-PAOX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Putrescine biosynthetic process grouped by PAOX-low versus PAOX-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAOX→partner) and Y-score (partner→PAOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Putrescine biosynthetic process →	-0.237	-1.466	.003	<.001	3	15
OVARY	Positive regulation of amine metabolic process →	-0.227	-1.103	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.073	+0.921	<.001	<.001	3	13
BLOOD_Lymphoma	Negative regulation of respiratory burst involved in inflammatory response →	+0.116	+1.226	<.001	<.001	3	13
BLOOD_Lymphoma	Negative regulation of respiratory burst →	+0.116	+1.226	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.112	+0.770	<.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,881 associations by consensus.

Putrescine biosynthetic process by PAOX expression — LIVER

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