PANX3

Across TCGA patient cohorts, PANX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,632 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PANX3-associated GO terms across cancer lineages are Intracellular protein transmembrane transport, tRNA metabolic process, and Positive regulation of mitotic cell cycle. Each is linked with PANX3 in more than 16 cancer types. Because this analysis shows association rather than direction, both PANX3-to-partner and partner-to-PANX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular protein transmembrane transport grouped by PANX3-low versus PANX3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PANX3→partner) and Y-score (partner→PANX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Intracellular protein transmembrane transport →	+0.064	+0.176	<.001	<.001	3	17
STAD	tRNA metabolic process →	+0.065	+0.220	<.001	<.001	3	17
STAD	Positive regulation of mitotic cell cycle →	+0.061	+0.221	<.001	<.001	3	17
ESCA	Ribose phosphate biosynthetic process →	+0.065	+0.311	<.001	<.001	3	17
STAD	Methylation →	+0.058	+0.220	<.001	<.001	3	17
STAD	Negative regulation of mRNA processing →	+0.064	+0.215	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,632 associations by consensus.

Intracellular protein transmembrane transport by PANX3 expression — STAD

Explore this box plot interactively →