PANX3

Across TCGA cell cohorts, PANX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 397 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PANX3-associated GO terms across cancer lineages are Mitochondrial electron transport, NADH to ubiquinone, Regulation of protein sumoylation, and Regulation of microtubule nucleation. Each is linked with PANX3 in more than 4 cancer types. Because this analysis shows association rather than direction, both PANX3-to-partner and partner-to-PANX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, NADH to ubiquinone grouped by PANX3-low versus PANX3-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PANX3→partner) and Y-score (partner→PANX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Mitochondrial electron transport, NADH to ubiquinone →	+0.057	+0.139	.004	.004	3	5
STOMACH	Regulation of protein sumoylation →	+0.113	+0.191	<.001	.006	3	4
SKIN	Regulation of microtubule nucleation →	+0.069	+0.104	<.001	.001	3	4
LIVER	Chloride transmembrane transport →	-0.052	-0.205	.009	.006	3	4
STOMACH	Regulation of DNA repair →	+0.058	+0.173	<.001	.004	3	3
SKIN	mRNA cis splicing, via spliceosome →	+0.060	+0.096	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 397 associations by consensus.

Mitochondrial electron transport, NADH to ubiquinone by PANX3 expression — SKIN

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