PANK4

Across TCGA patient cohorts, PANK4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,203 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PANK4-associated proteins across cancer lineages are C1orf174, RPA1, and DNAJC8. Each is linked with PANK4 in more than 4 cancer types. Because this analysis shows association rather than direction, both PANK4-to-partner and partner-to-PANK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PANK4 versus C1orf174 in UCEC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PANK4→partner) and Y-score (partner→PANK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C1orf174 →	+0.409	+0.821	<.001	<.001	3	5
LSCC	RPA1 →	+0.374	+0.315	<.001	.002	3	5
GBM	DNAJC8 →	+0.286	+0.260	<.001	<.001	3	5
BRCA	FLAD1 →	-0.311	-0.501	.002	.001	3	4
GBM	PPP1R8 →	+0.205	+0.318	.001	<.001	3	4
GBM	EHMT1 →	+0.312	+0.295	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,203 associations by consensus.

PANK4 vs C1orf174 — UCEC

Explore this scatter interactively →