PAN2

Across TCGA patient cohorts, PAN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,729 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAN2-associated proteins across cancer lineages are SMARCC2, SART3, and SMC1A. Each is linked with PAN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PAN2-to-partner and partner-to-PAN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAN2 versus SMARCC2 in BRCA, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAN2→partner) and Y-score (partner→PAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SMARCC2 →	+0.308	+0.779	<.001	<.001	3	8
GBM	SART3 →	+0.269	+0.443	<.001	<.001	3	8
GBM	SMC1A →	+0.391	+0.432	<.001	<.001	3	7
GBM	SMC3 →	+0.261	+0.259	<.001	.003	3	7
LSCC	THOC5 →	+0.277	+0.523	<.001	<.001	3	6
GBM	PDS5B →	+0.255	+0.312	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,729 associations by consensus.

PAN2 vs SMARCC2 — BRCA

Explore this scatter interactively →