PAN2

Across TCGA cell cohorts, PAN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,830 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PAN2-associated GO terms across cancer lineages are Chiasma assembly, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and mRNA splice site recognition. Each is linked with PAN2 in more than 17 cancer types. Because this analysis shows association rather than direction, both PAN2-to-partner and partner-to-PAN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chiasma assembly grouped by PAN2-low versus PAN2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAN2→partner) and Y-score (partner→PAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chiasma assembly →	+0.363	+1.277	.003	<.001	3	18
OESOPHAGUS	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.161	+1.632	.001	<.001	3	18
LARGE_INTESTINE	mRNA splice site recognition →	+0.149	+1.336	<.001	<.001	3	17
URINARY_TRACT	Taurine biosynthetic process →	+0.944	+1.513	.002	<.001	3	17
URINARY_TRACT	Alkanesulfonate biosynthetic process →	+0.944	+1.513	.002	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	RNA catabolic process →	+0.082	+1.905	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,830 associations by consensus.

Chiasma assembly by PAN2 expression — BONE

Explore this box plot interactively →