PAMR1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PAMR1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,797 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PAMR1-associated genes across cancer lineages are IRAG1, LYVE1, and TMEM47. Each is linked with PAMR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PAMR1-to-partner and partner-to-PAMR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAMR1 versus IRAG1 in CCRCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAMR1→partner) and Y-score (partner→PAMR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCIRAG1 →+1.141+0.859<.001<.00137
GBMLYVE1 →+1.995+0.684<.001<.00136
HNSCTMEM47 →+1.015+0.664.004<.00136
BRCADIPK2B →+0.803+0.701<.001<.00136
UCECLMOD1 →+1.789+0.652<.001<.00136
CCRCCNR2F2-AS1 →+0.940+0.780<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,797 associations by consensus.

PAMR1 vs IRAG1 — CCRCC

Per-sample scatter of PAMR1 vs IRAG1 in CCRCC (Pearson r = 0.49).

Explore this scatter interactively →

Exploration