Across TCGA patient cohorts, PALM3 mutation is significantly associated with the RNA expression of many other genes, with 2,511 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PALM3-associated genes across cancer lineages are RNA5SP86, RN7SL560P, and KLRC4. Each is linked with PALM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PALM3-to-partner and partner-to-PALM3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PALM3→partner) and Y-score (partner→PALM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP86 →	+0.829	+4.821	<.001	.003	3	2
COAD	RN7SL560P →	+0.278	+3.321	<.001	.008	3	2
UCEC	KLRC4 →	+0.163	+1.930	<.001	.002	3	2
UCEC	RNU6-5P →	+0.394	+1.854	.001	<.001	3	2
UCEC	TRBJ2-2P →	+1.007	+1.921	<.001	.002	3	2
UCEC	IGHD2-2 →	+0.877	+1.543	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,511 associations by consensus.

Exploration

PALM3 survival (RNA) · tumor vs normal (RNA) · all PALM3 data types