Across TCGA cell cohorts, PALM3 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PALM3-associated genes across cancer lineages are C12orf42, C8orf34, and DPEP2NB. Each is linked with PALM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PALM3-to-partner and partner-to-PALM3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PALM3→partner) and Y-score (partner→PALM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C12orf42 →	+0.200	+4.222	<.001	.007	3	1
BLOOD_Leukemia	C8orf34 →	+0.114	+3.769	<.001	.008	3	1
BLOOD_Leukemia	DPEP2NB →	+0.064	+3.951	<.001	.005	2	1
BLOOD_Leukemia	INSM2 →	+0.311	+3.769	<.001	.008	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

PALM3 survival (RNA) · tumor vs normal (RNA) · all PALM3 data types