PALLD

Across TCGA patient cohorts, PALLD protein abundance is significantly associated with the RNA expression of many other genes, with 15,108 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PALLD-associated genes across cancer lineages are ACTA2, CCN2, and CALD1. Each is linked with PALLD in more than 9 cancer types. Because this analysis shows association rather than direction, both PALLD-to-partner and partner-to-PALLD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PALLD versus ACTA2 in OV, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PALLD→partner) and Y-score (partner→PALLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ACTA2 →	+2.135	+0.930	<.001	<.001	3	10
OV	CCN2 →	+1.413	+0.649	<.001	<.001	3	10
BRCA	CALD1 →	+1.234	+0.803	<.001	<.001	3	10
UCEC	CNN1 →	+2.504	+0.874	<.001	<.001	3	10
OV	TPM1 →	+0.996	+0.838	<.001	<.001	3	10
OV	CDH11 →	+1.623	+0.940	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,108 associations by consensus.

PALLD vs ACTA2 — OV

Explore this scatter interactively →