PALLD

Across TCGA cell cohorts, PALLD mutation is significantly associated with the RNA expression of many other genes, with 222 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PALLD-associated genes across cancer lineages are GALNTL5, CST9, and CES3. Each is linked with PALLD in more than 1 cancer types. Because this analysis shows association rather than direction, both PALLD-to-partner and partner-to-PALLD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALNTL5 grouped by PALLD-low versus PALLD-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PALLD→partner) and Y-score (partner→PALLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GALNTL5 →	+0.045	+3.544	<.001	.009	3	2
LUNG_NSCLC_LUAD	CST9 →	+0.069	+3.544	<.001	.009	3	2
LARGE_INTESTINE	CES3 →	+1.594	+2.628	<.001	.002	3	2
SOFT_TISSUE	GPR152 →	+0.010	+4.635	.009	.003	3	1
SOFT_TISSUE	GPR139 →	+0.016	+4.369	.004	.008	3	1
SOFT_TISSUE	NPSR1 →	+0.265	+4.222	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 222 associations by consensus.

GALNTL5 by PALLD expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →