PALD1

Across TCGA patient cohorts, PALD1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,109 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PALD1-associated genes across cancer lineages are CX3CR1, ADAMTSL2, and YY1P1. Each is linked with PALD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PALD1-to-partner and partner-to-PALD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PALD1 versus CX3CR1 in BRCA, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PALD1→partner) and Y-score (partner→PALD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CX3CR1 →	+1.468	+0.249	<.001	<.001	3	8
UCEC	ADAMTSL2 →	+1.254	+0.382	<.001	<.001	3	7
UCEC	YY1P1 →	+1.326	+0.358	<.001	<.001	3	7
LSCC	FGL2 →	+0.913	+0.267	<.001	<.001	3	7
UCEC	LMO2 →	+0.684	+0.328	.003	.003	3	7
GBM	DOCK10 →	+0.920	+0.382	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,109 associations by consensus.

PALD1 vs CX3CR1 — BRCA

Explore this scatter interactively →