PAK1IP1

Across TCGA patient cohorts, PAK1IP1 mutation is significantly associated with the RNA expression of many other genes, with 1,076 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PAK1IP1-associated genes across cancer lineages are RNU6ATAC30P, MSANTD2P1, and YPEL5P1. Each is linked with PAK1IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAK1IP1-to-partner and partner-to-PAK1IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6ATAC30P grouped by PAK1IP1-low versus PAK1IP1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAK1IP1→partner) and Y-score (partner→PAK1IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6ATAC30P →	+0.629	+4.605	<.001	.004	3	2
BLCA	MSANTD2P1 →	+0.068	+5.017	<.001	.002	3	2
BLCA	YPEL5P1 →	+0.139	+5.018	<.001	.004	3	2
BLCA	RN7SL447P →	+0.193	+4.497	<.001	.009	3	2
BLCA	RNU6-113P →	+0.871	+6.874	<.001	<.001	3	2
COAD	OR5J7P →	+0.314	+7.741	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,076 associations by consensus.

RNU6ATAC30P by PAK1IP1 expression — BLCA

Explore this box plot interactively →