PAK1IP1

Across TCGA cell cohorts, PAK1IP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,774 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PAK1IP1-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, rRNA 5'-end processing, and Positive regulation of rRNA processing. Each is linked with PAK1IP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both PAK1IP1-to-partner and partner-to-PAK1IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by PAK1IP1-low versus PAK1IP1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAK1IP1→partner) and Y-score (partner→PAK1IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of RNA export from nucleus →	+0.163	+0.977	<.001	.005	3	18
PANCREAS	rRNA 5'-end processing →	+0.123	+0.951	<.001	<.001	3	17
OESOPHAGUS	Positive regulation of rRNA processing →	+0.155	+1.192	<.001	.002	3	17
BONE	Maturation of SSU-rRNA →	+0.129	+0.767	<.001	.001	2	18
PANCREAS	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.123	+0.951	<.001	<.001	3	17
PANCREAS	DNA replication initiation →	+0.165	+1.139	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,774 associations by consensus.

Negative regulation of RNA export from nucleus by PAK1IP1 expression — LIVER

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