PAIP2B

Across TCGA cell cohorts, PAIP2B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,227 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PAIP2B-associated GO terms across cancer lineages are Positive regulation of DNA repair, Regulation of syncytium formation by plasma membrane fusion, and Calcium ion transport. Each is linked with PAIP2B in more than 12 cancer types. Because this analysis shows association rather than direction, both PAIP2B-to-partner and partner-to-PAIP2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by PAIP2B-low versus PAIP2B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAIP2B→partner) and Y-score (partner→PAIP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA repair →	+0.066	+0.813	<.001	<.001	3	13
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.118	+1.202	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Calcium ion transport →	-0.073	-0.939	<.001	<.001	3	13
BONE	Positive regulation of double-strand break repair via homologous recombination →	+0.080	+0.972	<.001	<.001	3	13
BONE	Extracellular structure organization →	-0.186	-0.910	<.001	<.001	3	12
BONE	External encapsulating structure organization →	-0.186	-0.943	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,227 associations by consensus.

Positive regulation of DNA repair by PAIP2B expression — BONE

Explore this box plot interactively →