PAIP2

Across TCGA patient cohorts, PAIP2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,978 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PAIP2-associated genes across cancer lineages are EXOC6B, PEAR1, and TJP1. Each is linked with PAIP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PAIP2-to-partner and partner-to-PAIP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAIP2 versus EXOC6B in COAD, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAIP2→partner) and Y-score (partner→PAIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EXOC6B →	-0.522	-0.585	.004	.005	3	4
UCEC	PEAR1 →	-0.573	-0.260	.001	<.001	3	4
COAD	TJP1 →	-0.708	-0.389	.008	.008	3	3
LUAD	CDC42BPA →	-0.868	-0.288	.001	<.001	3	3
COAD	PTPN21 →	-0.459	-0.461	.006	.007	3	3
LUAD	PRX →	-0.577	-0.294	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,978 associations by consensus.

PAIP2 vs EXOC6B — COAD

Explore this scatter interactively →