PAIP2

Across TCGA cell cohorts, PAIP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,272 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PAIP2-associated GO terms across cancer lineages are Protein localization to cilium, DNA replication-dependent chromatin disassembly, and Nucleotide-excision repair. Each is linked with PAIP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both PAIP2-to-partner and partner-to-PAIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by PAIP2-low versus PAIP2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAIP2→partner) and Y-score (partner→PAIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein localization to cilium →	+0.061	+0.644	<.001	.004	3	11
BREAST	DNA replication-dependent chromatin disassembly →	+0.087	+0.714	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair →	+0.068	+0.705	.001	.002	3	11
BLOOD_Myeloma	Regulation of centriole elongation →	+0.086	+0.656	.003	.002	3	10
BLOOD_Myeloma	Protein localization to nucleus →	+0.062	+0.686	<.001	.003	3	10
URINARY_TRACT	Chromosomal DNA methylation maintenance following DNA replication →	+0.180	+0.764	.007	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,272 associations by consensus.

Protein localization to cilium by PAIP2 expression — URINARY_TRACT

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