PAIP1

Across TCGA pan-cancer cohorts, PAIP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PAIP1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PAIP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PAIP1 expression acts as an unfavorable survival marker.

CCRCC, PDAC, and LUAD are the cancer types where PAIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.383	1.000	.003	28	view →
PDAC	OS	Tertile	All	0.356	0.705	.001	17	view →
LUAD	DFS	Quartile	All	0.420	0.791	.005	16	view →
HNSC	OS	Quartile	All	0.270	1.000	.021	6	view →
UCEC	OS	Quartile	All	0.882	1.000	.033	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PAIP1–CCRCC (DFS)

Open the CCRCC breakdown →