Across TCGA pan-cancer cohorts, PAICSP2 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated PAICSP2 data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PAICSP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PAICSP2 expression acts as an unfavorable survival marker, although some lineages such as MESO and BRCA show a favorable association.
KIRC, LIHC, and TGCT are the cancer types where PAICSP2 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.