PAH

Across TCGA patient cohorts, PAH RNA expression is significantly associated with the protein abundance of many other proteins, with 14,404 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PAH-associated proteins across cancer lineages are NIBAN2, ACTR3, and SART3. Each is linked with PAH in more than 4 cancer types. Because this analysis shows association rather than direction, both PAH-to-partner and partner-to-PAH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAH versus NIBAN2 in LUAD, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAH→partner) and Y-score (partner→PAH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NIBAN2 →	-0.303	-1.194	<.001	<.001	3	5
PDAC	ACTR3 →	-0.227	-0.694	<.001	.001	3	5
LSCC	SART3 →	+0.204	+0.672	.002	<.001	3	5
HNSC	MYEF2 →	+0.581	+0.480	<.001	.001	3	4
HNSC	MYEF2_S17 →	+1.063	+0.566	<.001	.005	3	4
BRCA	THNSL1 →	+0.452	+0.569	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,404 associations by consensus.

PAH vs NIBAN2 — LUAD

Explore this scatter interactively →