PAGE4

Across TCGA patient cohorts, PAGE4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,668 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible PAGE4-associated GO terms across cancer lineages are Regulation of DNA-templated transcription elongation, Cellular respiration, and Obsolete ncRNA transcription. Each is linked with PAGE4 in more than 9 cancer types. Because this analysis shows association rather than direction, both PAGE4-to-partner and partner-to-PAGE4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription elongation grouped by PAGE4-low versus PAGE4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE4→partner) and Y-score (partner→PAGE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA-templated transcription elongation →	+0.049	+0.199	<.001	<.001	3	10
STAD	Cellular respiration →	+0.082	+0.279	<.001	<.001	3	10
STAD	Obsolete ncRNA transcription →	+0.043	+0.194	<.001	<.001	3	10
STAD	Mitochondrial translation →	+0.052	+0.203	<.001	<.001	3	10
STAD	Positive regulation of mitotic cell cycle →	+0.040	+0.189	<.001	<.001	3	10
STAD	tRNA metabolic process →	+0.039	+0.188	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,668 associations by consensus.

Regulation of DNA-templated transcription elongation by PAGE4 expression — STAD

Explore this box plot interactively →