PAGE4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PAGE4 RNA expression is significantly associated with the go_rna of many other GO terms, with 507 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PAGE4-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Nucleoside triphosphate biosynthetic process, and Vacuole organization. Each is linked with PAGE4 in more than 3 cancer types. Because this analysis shows association rather than direction, both PAGE4-to-partner and partner-to-PAGE4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by PAGE4-low versus PAGE4-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE4→partner) and Y-score (partner→PAGE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSEstablishment of protein localization to organelle →+0.027+0.516.009.00934
BLOOD_LymphomaNucleoside triphosphate biosynthetic process →+0.049+0.684.001.00934
UPPER_AERODIGESTIVE_TRACTVacuole organization →+0.046+0.064.002.00634
LUNG_SCLCEstablishment of protein localization to membrane →+0.033+0.218.003.00634
CNSHeterochromatin formation →+0.038+0.364.001.00734
OVARYAngiogenesis →-0.053-0.187.001.00434
Each partner links to its Q-omics profile. Showing the 6 strongest of 507 associations by consensus.

Establishment of protein localization to organelle by PAGE4 expression — CNS

Box plot of Establishment of protein localization to organelle in PAGE4-low vs PAGE4-high samples in CNS.

Explore this box plot interactively →

Exploration