PAGE1

Across TCGA pan-cancer cohorts, PAGE1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated PAGE1 data layer compared with 2 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher PAGE1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PAGE1 expression acts as an unfavorable survival marker, although some lineages such as LGG and ACC show a favorable association.

KICH, KIRP, and COAD are the cancer types where PAGE1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.790	0.981	<.001	108	view →
KIRP	DFS	Tertile	All	0.711	0.883	<.001	105	view →
COAD	DFS	Tertile	II,III,IV	0.293	0.592	.006	61	view →
LIHC	OS	Tertile	All	0.557	0.733	<.001	47	view →
PAAD	OS	Tertile	II,III,IV	0.452	0.623	.005	42	view →
KIRC	DFS	Tertile	All	0.490	0.654	.009	39	view →
UVM	DFS	Tertile	III,IV	0.032	0.727	<.001	36	view →
THCA	OS	Tertile	All	0.982	0.994	.006	30	view →
LUSC	DFS	Quartile	All	0.529	0.745	.006	25	view →
PRAD	OS	Tertile	All	0.969	0.996	.013	12	view →
SKCM	DFS	Tertile	IV	0.057	0.571	.004	9	view →
MESO	OS	Tertile	II,III,IV	0.396	0.575	.037	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

PAGE1–KICH (OS)

Open the KICH breakdown →