PAGE1

Across TCGA pan-cancer cohorts, PAGE1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PAGE1 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher PAGE1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PAGE1 expression acts as an unfavorable survival marker.

PAAD and UCEC are the cancer types where PAGE1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.132	0.613	.002	15	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PAGE1–PAAD (OS)

Open the PAAD breakdown →