PAFAH2

Across TCGA patient cohorts, PAFAH2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,815 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAFAH2-associated genes across cancer lineages are GPR161, BOLA3-AS1, and GNB3. Each is linked with PAFAH2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PAFAH2-to-partner and partner-to-PAFAH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAFAH2 versus GPR161 in UCEC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAFAH2→partner) and Y-score (partner→PAFAH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GPR161 →	-0.823	-0.354	.006	.002	3	6
OV	BOLA3-AS1 →	-0.739	-0.500	<.001	<.001	3	6
UCEC	GNB3 →	-0.702	-0.311	<.001	.001	3	5
LUAD	HMGCL →	+0.404	+0.270	<.001	<.001	3	5
OV	UNK →	-0.560	-0.366	.002	.003	3	5
UCEC	SRSF12 →	-0.811	-0.360	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,815 associations by consensus.

PAFAH2 vs GPR161 — UCEC

Explore this scatter interactively →