PAFAH2

Across TCGA patient cohorts, PAFAH2 protein abundance is significantly associated with the protein abundance of many other proteins, with 21,858 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAFAH2-associated proteins across cancer lineages are HMGCL, ABCD3, and STX3. Each is linked with PAFAH2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PAFAH2-to-partner and partner-to-PAFAH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAFAH2 versus HMGCL in UCEC, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAFAH2→partner) and Y-score (partner→PAFAH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HMGCL →	+0.412	+0.337	<.001	<.001	3	9
BRCA	ABCD3 →	+0.622	+0.350	<.001	<.001	3	8
GBM	STX3 →	+0.697	+0.439	<.001	<.001	3	8
LUAD	ACAA1 →	+0.391	+0.353	<.001	<.001	3	7
BRCA	RBM47 →	+0.393	+0.257	<.001	<.001	3	7
LSCC	ASL →	+0.369	+0.224	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,858 associations by consensus.

PAFAH2 vs HMGCL — UCEC

Explore this scatter interactively →