PAFAH1B2

Across TCGA patient cohorts, PAFAH1B2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,919 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PAFAH1B2-associated genes across cancer lineages are MPZL3, DUS1L, and REXO2. Each is linked with PAFAH1B2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PAFAH1B2-to-partner and partner-to-PAFAH1B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAFAH1B2 versus MPZL3 in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAFAH1B2→partner) and Y-score (partner→PAFAH1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MPZL3 →	+0.699	+0.211	<.001	<.001	3	5
OV	DUS1L →	-0.517	-0.578	<.001	<.001	3	4
OV	REXO2 →	+0.545	+0.489	<.001	<.001	3	4
BRCA	TBRG1 →	+0.532	+0.246	.001	.001	3	4
BRCA	TLCD5 →	+0.499	+0.205	<.001	.001	3	4
BRCA	RBM7 →	+0.429	+0.230	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,919 associations by consensus.

PAFAH1B2 vs MPZL3 — LSCC

Explore this scatter interactively →