PAFAH1B2

Across TCGA patient cohorts, PAFAH1B2 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PAFAH1B2-associated genes across cancer lineages are MIG-6 and EGFR_pY1173. Each is linked with PAFAH1B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAFAH1B2-to-partner and partner-to-PAFAH1B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIG-6 grouped by PAFAH1B2-low versus PAFAH1B2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAFAH1B2→partner) and Y-score (partner→PAFAH1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIG-6 →	+0.136	+2.820	.025	.036	2	1
UCEC	EGFR_pY1173 →	+0.121	+2.833	.013	.035	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MIG-6 by PAFAH1B2 expression — UCEC

Explore this box plot interactively →