PAF1

Across TCGA patient cohorts, PAF1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,016 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PAF1-associated genes across cancer lineages are TBCB, COQ8B, and RBM42. Each is linked with PAF1 in more than 33 cancer types. Because this analysis shows association rather than direction, both PAF1-to-partner and partner-to-PAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAF1 versus TBCB in ACC, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAF1→partner) and Y-score (partner→PAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	TBCB →	+0.954	+1.235	<.001	<.001	3	34
UCS	COQ8B →	+1.056	+1.166	.001	<.001	3	34
ACC	RBM42 →	+1.043	+1.195	<.001	<.001	3	34
UCS	NFKBIB →	+0.985	+0.795	<.001	<.001	3	33
OV	YIF1B →	+0.869	+0.813	<.001	<.001	3	33
ACC	AKAP8L →	+0.960	+1.049	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,016 associations by consensus.

PAF1 vs TBCB — ACC

Explore this scatter interactively →