PAEP

Across TCGA pan-cancer cohorts, PAEP mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PAEP data layer compared with 28 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PAEP mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated PAEP expression acts as an unfavorable survival marker.

LUAD, PDAC, and LSCC are the cancer types where PAEP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.657	1.000	.005	11	view →
PDAC	DFS	Quartile	All	0.173	0.629	.047	3	view →
LSCC	DFS	Tertile	II,III,IV	0.256	0.743	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PAEP–LUAD (OS)

Open the LUAD breakdown →