PAEP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PAEP RNA expression is significantly associated with the protein abundance of many other proteins, with 12,755 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PAEP-associated proteins across cancer lineages are NCF2, NNMT, and PLAU. Each is linked with PAEP in more than 4 cancer types. Because this analysis shows association rather than direction, both PAEP-to-partner and partner-to-PAEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAEP versus NCF2 in COAD, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAEP→partner) and Y-score (partner→PAEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADNCF2 →+0.457+0.521<.001.00135
CCRCCNNMT →+0.746+1.283<.001<.00135
COADPLAU →+1.177+1.310<.001.00135
BRCAFOSL2_S120 →+0.738+0.959<.001.00235
HNSCLARP4_S583 →+0.354+1.256<.001<.00135
PDACCDA →+0.573+1.508.008.00535
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,755 associations by consensus.

PAEP vs NCF2 — COAD

Per-sample scatter of PAEP vs NCF2 in COAD (Pearson r = 0.48).

Explore this scatter interactively →

Exploration