PADI3

Across TCGA patient cohorts, PADI3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,602 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PADI3-associated genes across cancer lineages are MIR3972, PRKD3, and TPPP3. Each is linked with PADI3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PADI3-to-partner and partner-to-PADI3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PADI3 versus MIR3972 in LSCC, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PADI3→partner) and Y-score (partner→PADI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MIR3972 →	+2.509	+1.947	<.001	<.001	3	3
LSCC	PRKD3 →	-0.274	-0.774	.002	.005	3	2
HNSC	TPPP3 →	+1.267	+0.897	<.001	<.001	3	2
HNSC	TOMM5 →	-0.522	-0.730	.004	.005	3	2
LSCC	SLC36A4 →	-0.659	-1.251	<.001	<.001	3	2
LSCC	GJB4 →	+1.615	+1.806	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,602 associations by consensus.

PADI3 vs MIR3972 — LSCC

Explore this scatter interactively →