PADI2

Across TCGA patient cohorts, PADI2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,529 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PADI2-associated genes across cancer lineages are BCL2A1, PLAUR, and CSF3R. Each is linked with PADI2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PADI2-to-partner and partner-to-PADI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PADI2 versus BCL2A1 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PADI2→partner) and Y-score (partner→PADI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BCL2A1 →	+1.342	+0.699	<.001	<.001	3	7
UCEC	PLAUR →	+1.047	+0.812	<.001	<.001	3	6
GBM	CSF3R →	+1.070	+1.047	<.001	<.001	3	6
GBM	PIK3R5 →	+0.876	+0.573	<.001	.005	3	6
UCEC	PTAFR →	+1.165	+0.908	<.001	<.001	3	6
PDAC	CXCL8 →	+1.666	+0.520	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,529 associations by consensus.

PADI2 vs BCL2A1 — BRCA

Explore this scatter interactively →