PADI2

Across TCGA cell cohorts, PADI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,013 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PADI2-associated GO terms across cancer lineages are Negative regulation of lymphocyte chemotaxis, Positive regulation of viral process, and Positive regulation of post-translational protein modification. Each is linked with PADI2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PADI2-to-partner and partner-to-PADI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of lymphocyte chemotaxis grouped by PADI2-low versus PADI2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PADI2→partner) and Y-score (partner→PADI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of lymphocyte chemotaxis →	+1.483	+2.639	<.001	<.001	3	9
STOMACH	Positive regulation of viral process →	+0.062	+0.969	.003	.002	3	7
LUNG_SCLC	Positive regulation of post-translational protein modification →	+0.060	+1.532	.001	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Membrane biogenesis →	+0.076	+0.943	<.001	.002	3	6
OESOPHAGUS	T cell selection →	+0.125	+2.129	.008	.004	2	7
UPPER_AERODIGESTIVE_TRACT	Intracellular protein transmembrane transport →	+0.046	+0.922	.007	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,013 associations by consensus.

Negative regulation of lymphocyte chemotaxis by PADI2 expression — PANCREAS

Explore this box plot interactively →