PADI1

Across TCGA patient cohorts, PADI1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,894 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PADI1-associated genes across cancer lineages are GNA15, PTK6, and FAM83A. Each is linked with PADI1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PADI1-to-partner and partner-to-PADI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PADI1 versus GNA15 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PADI1→partner) and Y-score (partner→PADI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GNA15 →	+0.994	+0.963	.008	.006	3	4
UCEC	PTK6 →	+1.424	+1.381	<.001	<.001	3	3
LSCC	FAM83A →	+1.805	+0.974	<.001	<.001	3	3
HNSC	DNAAF3 →	+0.528	+0.448	<.001	<.001	3	3
PDAC	LY6D →	+2.528	+0.793	<.001	<.001	3	3
PDAC	IL20RB →	+1.546	+0.816	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,894 associations by consensus.

PADI1 vs GNA15 — UCEC

Explore this scatter interactively →