PACSIN3

Across TCGA patient cohorts, PACSIN3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,729 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PACSIN3-associated genes across cancer lineages are DOK3, CFL2, and DMD. Each is linked with PACSIN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PACSIN3-to-partner and partner-to-PACSIN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PACSIN3 versus DOK3 in LSCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PACSIN3→partner) and Y-score (partner→PACSIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOK3 →	-0.653	-0.427	<.001	<.001	3	4
HNSC	CFL2 →	+1.150	+0.914	<.001	<.001	3	4
HNSC	DMD →	+1.341	+0.726	<.001	<.001	3	4
LUAD	IL17RE →	+0.890	+0.378	.001	.001	3	4
HNSC	CRYAB →	+1.851	+0.792	<.001	<.001	3	3
CCRCC	MYCT1 →	+0.940	+0.379	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,729 associations by consensus.

PACSIN3 vs DOK3 — LSCC

Explore this scatter interactively →